Aflatoxin B1 Degradation Enzyme

Aflatoxins are secondary metabolites produced by certain Aspergillus fungi. They have strong teratogenic, carcinogenic, and mutagenic effects. Among them, Aflatoxin B1 is the most toxic and can seriously damage the digestive function and immune system of animals, resulting in reduced production performance such as animal feed conversion rate, and can accumulate in liver, kidney, muscle and other tissues, seriously endangering animal health and human food safety, and causing huge economic losses to related industries and animal husbandry production.

Aflatoxin is relatively stable to light, heat and acid. It can only be lysed when heated to 280-300℃. After autoclaving for 2 hours, the toxicity is reduced by 25% -33%, and the toxicity is reduced by 50% in 4 hours. The physical and chemical methods have various application defects removing aflatoxin. At present, the biodegradation of aflatoxin has become a safe, efficient and environmentally friendly method and has attracted much attention.

The effective component Aflatoxin B1 degradation enzyme acts on the bisfuran 8,9 series olefin ether bond of the toxic structure of Aflatoxin B1, and hydrolyzes the Aflatoxin B1 into non-toxic substances after oxidation.

Aflatoxin B1 degradation enzyme has the biological activity of specifically degradating Aflatoxin B1, decomposes and destroys the toxic group of aflatoxin molecules, and produces non-toxic degradation products. At the same time, the product has good removal of other mycotoxins. The function of this product can significantly reduce the damage of mycotoxins in feed materials to animals and give full play to the nutritional value of feed. This product is a kind of all organic green feed additives, which can completely decompose aflatoxins and reduce the secondary pollution of the toxins to the environment. It is suitable for chickens, pigs and other animals. 

Properly use Aflatoxin B1 degradation enzyme will enhance animals' health. The liver plays a protective role, and can effectively improve the animal's own immunity, will not remain in the animal's body, and can reduce the accumulation of toxic damage caused by aflatoxin to the human body through the food chain.

1. Most adsorbents only adsorb aflatoxin, and have almost no adsorption capacity for other mycotoxins such as zearalenone, vomiting toxin, T-2 toxin, etc.;

2. The adsorption properties of the adsorbent have no clear selectivity, and also have adsorption effect on nutrients such as vitamins, trace elements and amino acids, and the large dosage used dilutes and reduces the nutritional value of feed;

3. The effect of the adsorbent is unstable and low in efficiency. It will desorb in the digestive tract and cause secondary animal poisoning.

This product is a specific biological enzyme that can specifically and efficiently decompose aflatoxins in the feed, without destroying other ingredients in the feed, nor adsorbing trace elements and nutrients in the feed, ensuring the nutrients added to the feed is not wasted and excluded from the body. The product is fully organic, which is safer and will not cause adverse reactions such as animal constipation and lack of certain nutrients. It can be added in the feed for a long time.

1. Reduce the residue of Aflatoxin B1 in animals (internal organs, blood, muscle);

2. Protect the liver function and improve the body's immune performance;

3. Reduce subcutaneous bleeding caused by toxins and improve carcass quality.

1. Most adsorbents only adsorb aflatoxin, and have almost no adsorption capacity for other mycotoxins such as zearalenone, vomitoxin, T-2 toxin, etc.;

2. The adsorption properties of the adsorbent have no clear selectivity, and also have adsorption effect on nutrients such as vitamins, trace elements and amino acids, and the large dosage used dilutes and reduces the nutritional value of feed;

3. The effect of the adsorbent is unstable and low in efficiency. It will desorb in the digestive tract and cause secondary animal poisoning.

1. Enzymatically degrade toxic genes, change the molecular structure of mycotoxins, and degrade them into non-toxic and harmless metabolites, effectively eliminating the harm of mycotoxins to breeding animals.

2. The high-efficiency combination of mycotoxin degradation enzyme and degrading bacteria, the dual effect of mycotoxin degradation enzyme and probiotics.

3. Efficiently degrade a variety of mycotoxins. Adjust the intestinal micro-ecological balance, improve the body's immunity, and stabilize production performance.

1. Enzymatic degradation of toxic genes changes the molecular structure of mycotoxins and degrades them into non-toxic and harmless metabolites, effectively eliminating the harm of mycotoxins to breeding animals.

2. Efficiently degrade aflatoxin, zearalenone, vomitoxin and other mycotoxins, with high degradation rate.

3. The general mold release agent is of the adsorption type, which is not highly targeted, with unstable effect, large nutrients loss, and the adsorbed toxins are eliminated from the body and cause secondary pollution.

4. Mycotoxin B1 degradation enzyme is highly pertinent, and only degrades the corresponding mycotoxin without affecting the nutritional value of the feed. Moreover, the degradation products are pollution-free and will not cause secondary pollution when discharged from the body.

1. Guaranteed value of product composition analysis: Aflatoxin B1 decomposition enzyme ≥2000U/g, moisture ≤12.0%.

2. Sanitary indicators: lead ≤ 20.0 mg/kg, total arsenic ≤ 2.0 mg/kg, pickax ≤ 0.5 mg/kg, Escherichia coli ≤ 1.0x105/kg, Salmonella cannot be detected.

3. Composition of raw materials: aflatoxin B1 degradation enzyme, Bacillus subtilis, yeast, lactic acid bacteria, etc.

4. Application
   a. An efficient combination of mycotoxin degradation enzymes and degrading bacteria;
   b. The dual effects of mycotoxin degradation enzymes and probiotics;
   c. Efficiently degrade a variety of mycotoxins, adjust the intestinal microecological balance, improve the body's immunity, and stabilize production performance.

5. How to use:
   a. This product is suitable for all kinds of breeding livestock and poultry;
   b. The additive amount of the complete feed per ton is 50-100g.

6. Storage conditions and methods: store in a cool, ventilated, dry place, avoid mixing with toxic and harmful substances.

7. Matters needing attention:
   a. Mix evenly with feed, use as soon as possible after opening;
   b. It does not affect breeding management, disease prevention, and vaccination during use.

8. Net content: 20 kg/piece

9. Shelf life: 12 months

1. Daily prevention: 50-100 g/ton.

2. When mildew is severe: 100-200 g/ton. Aflatoxin B1 degradation enzyme is suitable for various animals.

3. Product specifications: 20 kg/bag

The detection rate is higher than standard, and a variety of molds exist simultaneously.

In 2018, 442 feeds and feed ingredients were collected from 19 provinces and cities including Beijing, Fujian, Anhui, Shandong, Guangdong, Henan, etc., and detected for aflatoxin B1, zearalenone, and vomitoxin that have a great impact on livestock production. The average detection rates of the three toxins were 96.72%, 92.92%, and 99.32%, respectively.